"Causes of acne: oil, hormones, bacteria; treatments: laser, plasma"
Causes of Acne and Its Influential Factors
Acne is one of the most common skin problems that many individuals encounter at different stages of life, particularly during adolescence. This issue can appear in the form of blackheads, whiteheads, inflammatory acne, cystic acne, or nodular acne. Acne typically occurs in areas with abundant sebaceous glands (oil-producing glands) such as the face, neck, chest, back, and shoulders.
Acne is a multifactorial skin issue that can be influenced by excessive sebum production, clogged pores, bacterial growth, hormonal changes, genetic factors, diet, and stress. Understanding these factors helps us choose more effective strategies for acne prevention and treatment. Proper skincare, a healthy diet, stress reduction, and using non-comedogenic products can play a significant role in controlling and improving acne.
Below is a detailed examination of the causes and influential factors of acne:
Medications
Certain medications, such as corticosteroids, antidepressants, anti-epileptic drugs, and testosterone supplements, can lead to acne. Additionally, the sudden discontinuation of some medications can result in inflammatory breakouts.
Inappropriate Cosmetic and Skincare Products
Using comedogenic (pore-clogging) cosmetic and skincare products can block skin pores and cause acne. Improper usage of these products, such as not cleansing makeup properly, can lead to oil and dirt buildup on the skin.
Continuous Contact with Irritants
Constantly touching the face with unclean hands, using a dirty phone, or wearing tight clothing that causes friction and sweating can block pores and worsen acne.
Environmental Factors
Exposure to air pollution, high humidity, or specific weather conditions can impact sebum production and increase the risk of acne. Direct sunlight can dry out the skin, prompting sebaceous glands to produce more oil in response.
Medications
Certain medications, such as corticosteroids, antidepressants, anti-epileptic drugs, and testosterone supplements, can lead to acne. Additionally, the sudden discontinuation of some medications can result in inflammatory breakouts.
Inappropriate Cosmetic and Skincare Products
Using comedogenic (pore-clogging) cosmetic and skincare products can block skin pores and cause acne. Improper usage of these products, such as not cleansing makeup properly, can lead to oil and dirt buildup on the skin.
Continuous Contact with Irritants
Constantly touching the face with unclean hands, using a dirty phone, or wearing tight clothing that causes friction and sweating can block pores and worsen acne.
Environmental Factors
Exposure to air pollution, high humidity, or specific weather conditions can impact sebum production and increase the risk of acne. Direct sunlight can dry out the skin, prompting sebaceous glands to produce more oil in response.
Excess Sebum (Skin Oil) Production
Sebum is an oily substance produced by sebaceous glands, playing a crucial role in maintaining the skin’s moisture and elasticity. Under normal conditions, sebum production helps regulate and protect the skin. However, when these glands become overly active, sebum production increases, leading to clogged pores. This excess oil can combine with dead skin cells, creating an environment conducive to bacterial growth.
- Factors influencing excessive sebum production: Hormonal changes, stress, certain medications, and genetic factors can increase sebaceous gland activity.
Clogged Skin Pores
The skin continuously regenerates, shedding dead cells from its surface. However, in some cases, these dead cells accumulate in the pores and, along with excess oil, block them. This blockage prevents sebum from reaching the skin’s surface, resulting in the formation of blackheads or whiteheads.
- Factors influencing clogged pores: Improper skin cleansing, using comedogenic (pore-clogging) cosmetic products, and hormonal changes.
Excessive Bacterial Growth (Propionibacterium acnes)
Naturally, the skin harbors bacteria called Propionibacterium acnes. Under normal circumstances, these bacteria are harmless. However, when pores are clogged, and excess sebum is produced, these bacteria multiply rapidly, causing inflammation and infection in hair follicles. This inflammation results in the formation of pustules and inflammatory acne.
- Influential factors: Excess sebum production, clogged pores, and environmental changes in the skin.
Hormonal Changes
Hormonal changes are one of the primary causes of acne. During puberty, pregnancy, menstrual cycles, or conditions such as polycystic ovary syndrome (PCOS), androgen hormones (e.g., testosterone) increase, stimulating sebaceous glands to produce more oil.
- Hormonal acne: This type usually appears around the jawline, chin, and mouth and is more common in adult women.
Genetic Factors
Genetics play a significant role in acne development. If parents or other family members have a history of severe acne, the likelihood of experiencing this issue increases in offspring. Genetics can influence sebum production, pore size, and the body’s response to inflammation.
Diet and Nutrition
Diet can also contribute to or exacerbate acne. Consuming excessive amounts of fatty foods, sugary items, dairy products, and foods with a high glycemic index can lead to increased sebum production and acne worsening.
- Triggering foods: Chocolate, dairy, processed foods, and fried items.
- Beneficial foods: A diet rich in vitamins (especially vitamin A and E), antioxidants, and omega-3 fatty acids can help improve acne.
Stress and Psychological Factors
Chronic stress can trigger or worsen acne. Stress increases cortisol levels, which stimulate sebaceous glands to produce more oil. Additionally, stress can weaken the immune system and intensify skin inflammations.
Types of Acne and Their Causes
- Whiteheads and Blackheads: Caused by clogged pores due to oil and dead skin cells.
- Inflammatory Acne: Results from excessive bacterial growth and inflammation in hair follicles.
- Cystic Acne: A severe form of acne caused by deep skin inflammation, which can lead to scarring.
Acne is a multifactorial skin condition influenced by excessive sebum production, clogged pores, bacterial growth, hormonal changes, genetic factors, diet, and stress. Understanding these factors helps us choose better strategies for preventing and treating acne. Proper skincare, a healthy diet, stress reduction, and the use of non-comedogenic products can play a significant role in managing and improving acne.
Treatment with Advanced Technologies
Skin Rejuvenation and Treating Skin Issues
Skin rejuvenation technologies are designed to improve texture, reduce wrinkles, and strengthen skin structure. Each of these technologies operates based on scientific mechanisms and innovative methods to safely and effectively regenerate the skin and boost collagen production. Below is an explanation of various technologies used in skin rejuvenation:
Cold and Hot Plasma Technology
Plasma, the fourth state of matter, is an ionized gas that stimulates skin tissues by releasing energy. Plasma technologies are offered in two types: cold plasma and hot plasma:
- Hot Plasma: In this method, the thermal energy of plasma is applied to the skin layers, creating controlled microscopic wounds. These wounds stimulate skin cells and increase collagen production, leading to firmer skin and reduced wrinkles. Hot plasma is beneficial for deep wrinkles and sagging skin.
- Cold Plasma: Cold plasma operates at lower energy and temperatures, improving skin texture and reducing pigmentation superficially. Cold plasma is particularly suitable for individuals with sensitive skin, as it stimulates the skin without causing deep damage and facilitates the rejuvenation process.
Carboxytherapy Technology
Carboxytherapy is a non-invasive skin rejuvenation method that involves injecting carbon dioxide gas beneath the skin. This gas, naturally present in the body, dilates blood vessels, increases blood flow, and enhances oxygen delivery to tissues. This process stimulates collagen production and improves skin elasticity. Carboxytherapy is effective for treating dark circles under the eyes, skin laxity, wrinkles, and improving skin tone and texture.
Nd:YAG Laser Technology (1064 nm Wavelength)
The Nd:YAG laser is a powerful laser with a wavelength of 1064nm that penetrates deeper into the skin. This laser stimulates collagen-producing cells in the deeper skin layers without damaging the surface, enhancing skin regeneration. Due to its low melanin absorption, the 1064nm wavelength is safer for all skin types, especially darker skin, and is used for wrinkle reduction, sagging treatment, and pigmentation removal.

Evaluating the Impact of Rejuvenation Technologies on Acne Treatment
Acne, one of the most common skin issues, is caused by factors such as excessive sebum production, clogged pores, bacterial growth, and inflammation. Treating acne can be complex, but advanced technologies like cold and hot plasma, carboxytherapy, and Nd:YAG lasers can help improve this condition. Below, each technology is individually analyzed for its positive effects, benefits, and related scientific studies in acne treatment:

Hot Plasma for Acne Treatment
Mechanism of Action: Hot plasma creates controlled heat and microscopic wounds, eliminating acne-causing bacteria and stimulating skin regeneration.
Positive Effects:
- Strong Disinfectant: The heat eliminates Propionibacterium acnes, the primary acne-causing bacteria.
- Skin Regeneration: Promotes the repair of damaged skin cells and reduces acne scars.
- Sebum Reduction: Controls sebum production by reducing sebaceous gland activity.
Advantages:
- Effective for severe acne, including cystic and inflammatory types.
- Simultaneously reduces active acne and improves scars caused by acne.
Scientific Studies: Research indicates that hot plasma significantly reduces acne lesions and improves skin texture.
Related Article:
Cold Plasma for Acne Treatment
Mechanism of Action: Cold plasma eliminates acne-causing bacteria and reduces inflammation through an electric field without generating high heat.
Positive Effects:
- Antibacterial Effect: Kills acne-causing bacteria without causing drug resistance.
- Inflammation Reduction: Helps reduce redness and inflammation associated with acne.
- Cell Regeneration: Repairs damaged skin cells and reduces acne scars.
Advantages:
- Fewer side effects, making it suitable for sensitive skin.
- Effective for active acne, particularly inflammatory and red types.
Scientific Studies: Studies demonstrate that cold plasma can significantly reduce inflammatory acne.
Related Article:
Carboxytherapy for Acne Treatment
Mechanism of Action: Carbon dioxide gas is injected into the skin, increasing blood flow and oxygen delivery to tissues, reducing inflammation, and aiding skin repair.
Positive Effects:
- Enhanced Blood Circulation: Improves oxygen delivery, accelerating acne healing.
- Inflammation Reduction: Reduces redness and inflammation caused by acne.
- Scar Repair: Stimulates collagen production and reduces acne scars.
Advantages:
- Non-invasive with minimal side effects.
- Effective for chronic acne resistant to conventional treatments.
Scientific Studies: Research shows that carboxytherapy reduces acne inflammation and accelerates lesion healing.
Related Article:
- Title: “Carboxytherapy as an Adjunctive Treatment for Acne and Scarring”
Nd:YAG Laser for Acne Treatment
Mechanism of Action: The Nd:YAG laser penetrates the dermis, reducing sebaceous gland activity to control oil production and killing acne-causing bacteria.
Positive Effects:
- Sebum Reduction: Controls acne by reducing sebaceous gland activity.
- Antibacterial Effect: Eliminates acne-causing bacteria without damaging surrounding tissues.
- Collagen Stimulation: Improves acne scars.
Advantages:
- Suitable for all skin types, particularly darker skin, with minimal risks.
- Effective for treating deep, cystic acne.
Scientific Studies: Research confirms that the Nd:YAG laser significantly reduces acne lesions and improves acne scars.
Related Article:
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